Team schedule for 2005-2006 Duquesne football
Conference record: 7-0-0 Overall: 14-1-0
WPIAL - Eastern Conference
* Conference games | PPD Postponed | F Forfeit
| Date | Opponent | Venue | Score |
|---|---|---|---|
| 8/27 1:30 pm | Greensburg Central Catholic | Duquesne | PPD |
| 9/2 7:30 pm | at North Catholic | Stone Field, North Park | W 45-0 |
| 9/10 1:30 pm | Clairton * | Duquesne | W 34-22 |
| 9/17 12 pm | at Riverview * | Riverside Park, Oakmont | W 13-7 |
| 9/24 1:30 pm | Wilkinsburg * | Duquesne | W 60-20 |
| 10/1 1:30 pm | Apollo-Ridge * | Duquesne | W 46-18 |
| 10/7 7:30 pm | at Springdale * | Veterans Memorial Field, Springdale | W 24-7 |
| 10/15 1:30 pm | Leechburg * | Duquesne | W 51-14 |
| 10/22 12 pm | at Serra Catholic * | Serra Catholic | W 34-7 |
| WPIAL Class A Playoffs: First Round | |||
| 10/29 1:30 pm | Jefferson-Morgan | Duquesne | W 49-0 |
| WPIAL Class A Playoffs: Quarterfinals | |||
| 11/4 7:30 pm | at Bentworth | Ringgold | W 48-7 |
| WPIAL Class A Playoffs: Semifinals | |||
| 11/11 7:30 pm | at Bishop Canevin | Belle Vernon | W 48-25 |
| WPIAL Class A Playoffs: Championship | |||
| 11/19 10:30 am | at Rochester | Heinz Field, Pittsburgh | W 14-6 |
| PIAA Class A Playoffs: Quarterfinals | |||
| 11/25 7 pm | Windber | East Allegheny | W 18-0 |
| PIAA Class A Playoffs: Semifinals | |||
| 12/2 7 pm | at Coudersport | Clarion University | W 33-2 |
| PIAA Class A Playoffs: Championship | |||
| 12/9 1 pm | at Southern Columbia | Hersheypark Stadium | L 50-19 |
